Laura Lambert Ph.D. is an Associate Consultant I in Physiology and Biomedical Engineering with joint appointments in Clinical Genomics and Biochemistry and Molecular Biology. Dr. Lambert is Director of the Mayo Clinic Functional Omics Resource, a laboratory which designs and executes functional genomic studies across the institution, and co-investigator of the Minnesota Functional Omics Resource. She has extensive experience in the development of precision cell and animal models for the study of rare genetic diseases from her previous roles as Director of the UAB Transgenic and Genetically Engineered Model Systems Core, Co-Lead of the Disease Modeling Unit in the UAB Center for Precision Animal Modeling, and Director of Models and Therapeutics in the UAB Precision Medicine Institute. This includes the application of these models to determine both pathogenicity of genetic changes as well as the investigation of novel therapeutic strategies for addressing patient needs in these ultra-rare conditions. Her research focuses on the use of gene therapy and other n=1 therapeutic approaches (e.g., exon skipping, ribozymes, CRISPRa/CRISPRi, prime editing, base editing) for rare genetic conditions, with a focus on nanoparticle-based delivery platforms. Her research has been funded by multiple NIH grants as well as many foundation based grants examining personalized medicine approaches, including her current work in n=1 nanoparticle mRNA delivery for the Wolverine Foundation in conjunction with Moderna.