Filippo Vairo is an Associate Consultant in the Department of Clinical Genomics and in the Center for Individualized Medicine (CIM) at Mayo Clinic where he is the Medical Director of the Program for Rare and Undiagnosed Disease (PRaUD). Also, he is Associate Professor of Medical Genetics at the Mayo Clinic College of Medicine and Science. He is the Associate Director of the Translational Omics Program (TOP) where he has been aiding in establishing several innovative techniques to assist patient practice in individualized medicine. Also, he is involved in developing and implementing novel methodologies for the identification of genetic variation causing disease and to functionally validate variant pathogenicity to ultimately increase the number of patients receiving a genetic diagnosis. Since 2008, Dr Vairo is one of the organizers of the Latin American School of Human and Medical Genetics and the Advanced Course on Diagnosis and Treatment of Inherited Diseases. He is member of the Editorial Board of the Journal of Inborn Errors of Metabolism and Screening, the Genetics and Molecular Biology journal, and affiliated member of the Brazilian National Academy of Medicine. He has experience in the area of clinical genetics, inborn errors of metabolism and lysosomal diseases, and precision medicine. Dr. Vairo's research interests include new diagnostic tools and translational medicine.